Gawd, these geezers at NFL must 'ate Lahndahn (actually the players do hate the trip - don't believe the hype) to put up these two bleedin' awful teams.
Each side is carrying injuries and Manuel coming in for the Bills is only one of a raft that makes this pick shaky. Ordinarily, Manuel wouldn't be too much of a problem, but injuries mean he has no-one to throw to, which is a shame, because the Jags' secondary couldn't stop a crisp packet blowing downfield. Expect LeSean McCoy and Charles Clay to be the entire Bills' offense.
I like Blake Bortles, but his protection is so dreadful (he's getting sacked nearly 3 times a game) that he's often forced into errors. Buffalo don't have a great pass rush, but they'll send everyone this afternoon. There's a decent secondary for the Bills too, so they'll eat up any mistakes. With no running game to support him, Bortles will be throwing a lot under pressure.
Not a game to savour, or bet the kids' college fund.
Pick: Buffalo Bills -3.5 @ 2
Pick: 1st TD LeSean McCoy @ 6.5
Pick: Anytime TD Charles Clay @ 2.38