The Giants' offensive line stank anyway and now they're missing personnel, which is a shame, because OBJ is finally breaking open games. It also means that the ground attack is limited (LA are awful defending the run) and Eli Manning is going to have be on his game. The Rams aren't bad against the pass, but Beckham can beat any cover, provided he has the ball!
New York's defense will need to bottle up Todd Gurley, who has flattered to deceive so far, as the secondary should be able to handle whatever Case Keenum throws their way under pressure from a decent pass rush.
It's a helluva long way from the west coast and as long as Eli can get the ball out and limit the turnovers, the G-Men should take this. It could be tight, so don't go mad.
Pick: Giants -2.5 @ 1.92
18-17, +0.31