hydroxychloroquine

Can someone post up the pdf in full?
People need to read it.

^^^^^trump is an ignorant idiot and has been saying as many things as possible in the hope that some of them are correct and he can claim he is a "stable genius".


Fire-and-Ice • March 30, 2020 2:35 PM BST
I said id report anyone who posts libellous stuff Dave

So when terry advocates behaviour that causes 100ks of mainly children to die each year, you are ok, but when someone points it out "omg libel"

dave, I know it's a different study, but same people, same hospital and from a quick look same methology.

Fire-and-Ice, you were the one urging for a bit of balance just the other day. Now the virologist urging cautioness instead of hyping a drug (with a number of known complications) as the wonder cure based on a non-peer reviewed study with potentially a number of methological problems up is the "expert naysayer"? Please...

from the - Ibrahima Sonko - Link (above) ...


The move comes after infectious diseases specialist Didier Raoult announced new clinical results that show 78 out of 80 patients treated with chloroquine recovered within five days

The five-day recovery time is “considerably” faster “than the usual 14 days and for some it can go up to 28 days if they recover at all,” the outlet highlighted.
-----------

That - 5-days - is identical to the recovery period of the 98-year-old man that I highlighted earlier - who was treated with a COMBINATION of ...

Hydroxychloroquine  with  Azithromycin

- as I posted - having got that information from the 98-year-old man's man's daughter - who posted as such (in the comments section underneath the newspapers website story) - and she also posted this Graph link to the use of the Drugs (as I also posted earlier)

https://www.mediterranee-infection.com/wp-content/uploads/2020/03/Hydroxychloroquine_final_DOI_IJAA-24-1038x553.jpg
------------

Those who listened to Trump's daily Bulletin yesterday - will have also heard him say ...

"We are trialling a combination of drug of - Hydroxychloroquine  with Azithromycin - on 1000 patients - that started yesterday, as the signs are good."

pdfs don't cut and paste well, anyone who wants can read it.  As I said it looks promising apart from no ideas about why it should work (that I can see).

You seem so certain giggilo and I doubt the the doctor posts on here and probably isnt a gambling man

Why dont you ask him what the odds are if you've lost your bottle
Add 20% on to the overround if you wish?

Terry accuses millions of people of mass murder (pilots, telecoms workers , doctors, scientists etc) . Is that libellous enough to report Fire.

Or maybe you would prefer to ignore those "libellous " posts & report people who point out that vaccines save lives?

What are the known complications edy.
Why is France sanctioning this drug?
You another who thinks they are wrong?

What odds you give me?

Why is it so hard for 'gamblers' who are so convinced they are right unable to price this up?

What are the known complications edy.
Why is France sanctioning this drug?
You another who thinks they are wrong?

What odds you give me?

Why is it so hard for 'gamblers' who are so convinced they are right unable to price this up?

I clicked that message once^^ no idea why it doubled

On a more serious note:

Convenience stores selling Easter eggs are facing interference from “heavy-handed” officials trying to restrict the range of goods they can sell under coronavirus curbs, a trade body says.
Some shops have been told by police and local councils that the chocolate eggs are considered non-essential goods.


BBC

Still not libellous Mexico, you arent very good at this are you?
I see all the usual doom-mongers/bullies are massed on here as per usual

Does your whatsapp group have a name?

Fire & Ice I'm not sure why you are getting into conversations with these lot because it is never worth it.

from what i have read it may help so is worth investigating but the french chap is not without his critics and has previously engaged in unethical behaviour.

https://blogs.sciencemag.org/pipeline/archives/2020/03/29/more-on-cloroquine-azithromycin-and-on-dr-raoult


i can recommend a chap on twitter - https://twitter.com/CT_Bergstrom

he is a professor in biology who already specialises in calling out bs, in the time of covid 19 he is especially busy.

Fire-and-Ice 30 Mar 20 13:44 
What are the known complications edy.
Why is France sanctioning this drug?
You another who thinks they are wrong?

What odds you give me?

Why is it so hard for 'gamblers' who are so convinced they are right unable to price this up?

You sound desperate for a bet,comeback to me when the racings on and you can lay me some horses not me laying you prices on some crazy addiction you obvously have then lets see who has the ''bottle''..

Why don't you price us up? You seem to be very convinced. What odds are you willing to take for it to be the wonder cure?

I'm not convinced it is the wonder cure, nor am I convinced it isn't though. I am simply pointing out that, according to at least expert, the scientific work of this group of authors might not provide as much conclusive evidence as some might hope.

Thanks for your post Onlooker.
Now I see why the usual suspects have assembled on this thread
Donald Trump seems to be going along with this study!

They can't stand it!
So predictable

Thats not how it works edy
I asked for odds, you give them.
Still stalling I see
Are you afraid that this might work and you will look mighty silly when I keep bringing the thread to the top?
Have some balls, price up this cure that has no chance

^ That really isn't fair re doom mongers etc, all the world aren't looking for ventilators for fun either, nothing wrong with a bit of cautious optimism mixed with realism.
Along with France,Ireland according to that professor seems to think it will "help", no a cure though.

he isn't "going along with the study" - his fda ordered a separate USA study as soon as the reports of some success came from China.

edy 30 Mar 20 13:49 
Why don't you price us up? You seem to be very convinced. What odds are you willing to take for it to be the wonder cure?

I'm not convinced it is the wonder cure, nor am I convinced it isn't though. I am simply pointing out that, according to at least expert, the scientific work of this group of authors might not provide as much conclusive evidence as some might hope.

Fire ad ice is thick as fcuk,he doesn't seem to understand that trils and sample trials unless big enough are not evidence of anything,thats why the US  are now doing a 1,000 sample trial instead of just giving it too every patient..

Fire-and-Ice • March 30, 2020 2:52 PM BST
Thats not how it works edy
I asked for odds, you give them.
Still stalling I see
Are you afraid that this might work and you will look mighty silly when I keep bringing the thread to the top?
Have some balls, price up this cure that has no chance

uhm...What part exactly of

"I'm not convinced it is the wonder cure, nor am I convinced it isn't though. I am simply pointing out that, according to at least expert, the scientific work of this group of authors might not provide as much conclusive evidence as some might hope."

did you fail to comprehend?

You see, if you seek to provoke me by speaking of my balls and manliness, you will be disappointed because I'm not your typical male who will feel hurt in his pride from that kind of gutter talk.

If you wish to get odds involved, you will have to be the one to come up with them.

You sound desperate for a bet,comeback to me when the racings on and you can lay me some horses not me laying you prices on some crazy addiction you obvously have then lets see who has the ''bottle''..

I want a bet on this study which you have dismissed giggilo.
Back that mouth of yours up with a real price!

and if you go look at jollywagman's post and link, it's another expert naysayer to add to Drosten.

Fire-and-Ice 30 Mar 20 13:58 
You sound desperate for a bet,comeback to me when the racings on and you can lay me some horses not me laying you prices on some crazy addiction you obvously have then lets see who has the ''bottle''..

I want a bet on this study which you have dismissed giggilo.
Back that mouth of yours up with a real price!


I havn't dismissed any stuy.it's just you are as thick as two shoet planks.

edy stop squirming. 'gutter talk' indeed. you seem so precious

if i ask for odds then the person who lays the odds tells me what they are.

what bookmakers do you go to?

anyway, its obvious you lot hunt in packs and try to derail optimistic threads by hounding people you disagree with.

None of you bet, that's for sure

short*

giggilo calling me thick. head in hands man
give me some odds you ball-less wonder!

For you in language you understand giggilo

I think this cure could work
You seem doubtful
In terms of odds how doubtful are you?

I'm not entirely sure how simply pointing out that, according to multiple experts, there might be some methological problems with the study is "hounding" people I disagree with.

Chloroquine helps cells uptake/intake zinc, zinc is alkaline and viruses prefer an acidic environment for reproduction/copying, zinc slows the reproduction rate,from my very very limited understanding zinc prevents viruses binding to their prefered protein within the cell,after binding they do a magical thing and copy there own code onto a polymerase chain, they use the ace2 enzyme to gain entry , so they disguise themselves at the door within an entry code, like a trojen type attack, once in they need to copy and chloroquine prevents this via increased zinc lowering or making the protein they want unavailable.The big problem is also the way good guy killer cells massively increase but can't get a proper ID on the bad dudes, adventually just start attacking anything that moves, bit like a bad regime in a bad country. Some advice is to eat whole grains, eat some yogurt as well to help maximise gut process. Just the old eat well, cut out junk, plenty good grub, exercise, simple basic stuff. If chloroquine was a silver bullet it would be in widespread use, (why not) imo, its perhaps because the last thing you need  when your nearly dead, have a massive lung infection and weakened immune system is being poisoned perhaps, it won't kill existing virus imvho, only slow repo. Happy to discuss, please no time wasters. Ps prevention is best here,why not wear a mask when at shops.

Fire-and-Ice 30 Mar 20 14:06 
For you in language you understand giggilo

I think this cure could work
You seem doubtful
In terms of odds how doubtful are you?

You appear to be seething about something no one will lay odds on or have any idea to price up even if they did as would be guessing,you think someones going to say ye you can have 20/1 on something they have no information about..Attetio seeker to go with trolling and an absolute seether of highest order..

edy Joined: 13 Dec 06
Replies: 22188530 Mar 20 14:06

I'm not entirely sure how simply pointing out that, according to multiple experts, there might be some methological problems with the study is "hounding" people I disagree with.

you referred to a single critic of the study and now there are multiple experts who disbelieve.
name them please.

the hounding was with reference to posters hunting in packs.
read the sentence again. you can't hound me alone can you?
ive got an idea you are deliberately playing dumb

Fire-and-Ice 30 Mar 20 14:13 
edy Joined: 13 Dec 06
Replies: 22188530 Mar 20 14:06

I'm not entirely sure how simply pointing out that, according to multiple experts, there might be some methological problems with the study is "hounding" people I disagree with.

you referred to a single critic of the study and now there are multiple experts who disbelieve.
name them please.

the hounding was with reference to posters hunting in packs.
read the sentence again. you can't hound me alone can you?
ive got an idea you are deliberately playing dumb


Another seeth,i refer you to previous seething reference post..

you referred to a single critic of the study and now there are multiple experts who disbelieve.
name them please.

edy • March 30, 2020 2:58 PM BST
and if you go look at jollywagman's post and link, it's another expert naysayer to add to Drosten.

you are welcome. It would be even better if you just read the posts of this thread to begin with instead of asking redundant questions because, in your state of obvious excitement, you obviously ignore half the posts to instead get your next strangely homoerotic comment in.

Good post Breadnbutter.

I'm not seething at all giggilo.
You cant back up the power of your conviction in terms of odds.
Nothing to be ashamed of mate
Most non-gamblers can't
Would've been easier if you had been more forth coming is all
I'm not trolling
I'm keeping an optimistic thread at the top of the forum
Its worth discussing

this post was lost in the bitching back and forth.

breadnbutter Joined: 29 Aug 06
Replies: 1048730 Mar 20 14:07 
Chloroquine helps cells uptake/intake zinc, zinc is alkaline and viruses prefer an acidic environment for reproduction/copying, zinc slows the reproduction rate,from my very very limited understanding zinc prevents viruses binding to their prefered protein within the cell,after binding they do a magical thing and copy there own code onto a polymerase chain, they use the ace2 enzyme to gain entry , so they disguise themselves at the door within an entry code, like a trojen type attack, once in they need to copy and chloroquine prevents this via increased zinc lowering or making the protein they want unavailable.The big problem is also the way good guy killer cells massively increase but can't get a proper ID on the bad dudes, adventually just start attacking anything that moves, bit like a bad regime in a bad country. Some advice is to eat whole grains, eat some yogurt as well to help maximise gut process. Just the old eat well, cut out junk, plenty good grub, exercise, simple basic stuff. If chloroquine was a silver bullet it would be in widespread use, (why not) imo, its perhaps because the last thing you need  when your nearly dead, have a massive lung infection and weakened immune system is being poisoned perhaps, it won't kill existing virus imvho, only slow repo. Happy to discuss, please no time wasters. Ps prevention is best here,why not wear a mask when at shops.

Thanks bb

Thank you Fire for your legal opinion.

So you are saying in is NOT.libel to accuse an innocent pilot , doctor of mass murder.


Glad we have that sorted Fire.
Great job BTW to appear on the forum for under a month but have already taken on the important tast of informing the Betfair staff if anyone is libellous in the hope that they have their posting privileges removed.

You must be very proud of your important policing role . Shame you were not around a few months ago. There use to be a poster called Dr Crippen who disappeared at about the same time you joined. The two of you could have worked together to keep this forum legal.

edy Joined: 13 Dec 06
Replies: 221886 30 Mar 20 14:16 
you referred to a single critic of the study and now there are multiple experts who disbelieve.
name them please.

edy • March 30, 2020 2:58 PM BST
and if you go look at jollywagman's post and link, it's another expert naysayer to add to Drosten.

you are welcome. It would be even better if you just read the posts of this thread to begin with instead of asking redundant questions because, in your state of obvious excitement, you obviously ignore half the posts to instead get your next strangely homoerotic comment in.

****-erotic? are you 12?
your passive-aggressiveness has been noted edy.

Fire-and-Ice 30 Mar 20 14:18 
I'm not seething at all giggilo.
You cant back up the power of your conviction in terms of odds.
Nothing to be ashamed of mate
Most non-gamblers can't
Would've been easier if you had been more forth coming is all
I'm not trolling
I'm keeping an optimistic thread at the top of the forum
Its worth discussing

Nope attention seeker,come back to me when horse racings on lets see what happens..i won't forget..

I can only comment what is libellous if I've read the comment Mexico.
Post up a link to the thread where your nemesis said he wanted people to die and I'll look at if for you

Just because everyone is losing their heads with panic, it doesn't give people the right
to say someone wants 1000s of people to die on a public forum

You seem overly preoccupied with this question of libel
Take it up with whoever runs this forum is my advice
Don't say libellous stuff and you'll be fine! Stop worrying so.

I can't wait for Fire-and-Ice to be vindictive to us going forward

I'm a backer giggilo

I'm gunna try horse-racing.
See if they'll quote me odds on this cure
Just imagine if it wins
I'll be quids in and the world will be joyous at the same time!
Surely that's what we all want!

Bottled it already,what a surprise..

I'll accommodate your bets on horses if you give me odds on this being the cure, giggilo
So, what odds?

ffs no one wants to win if it is a useless drug as that would be far more of a letdown than getting ten quid from you.

noted dave.
you won't give odds

btw I still do think you are a banned poster even though you've been here for a year.  You're style seems familiar.

your ffs

Fire

If someone has posted a view which will lead to the deaths of thousands of people then other users are allowed to say that those actions are a death wish.

The case Dave mention was many posts wanting all vaccines to stop. This action would result in many deaths - it is a very dangerous action.



Fire you seem very selective of which T&C you will report to Betfair to get users removed. I believe it is against the T&C to swear & abuse other users. You only seem to be bothered about post you consider to be libellous.
Still great news that such a new member to the forum has the decency and courage to police this forum & report posts. You are a true hero.

well, how will i sleep at night?

Mar 30, 2020 -- 9:40AM, dave1357 wrote:

btw I still do think you are a banned poster even though you've been here for a year.

Torquemada imo

Though Torquemada always uses lots of emojis...

Maybe not him after all.

Thank you mexico
I'm sorry, but you don't seem to have posted Terry's quote to want 1000s of death (on children iirc)
Let's not continue this waffle eh?
Or are you the type who MUST have the last word?

deaths*

^^maybe a talkmadder mutant strain?

edy you will soon get to a quarter of a million posts mate at this rate!
you must be so proud
i can do passive-aggressiveness too!

anyway wheres giggilo with his odds?

onlooker Joined: 18 Feb 03
Replies: 3329028 Mar 20 23:38 
On re-reading the article .

Hydroxychloroquine is being used in combination with - Azithromycin


This link shows a graph of study using hydroxychloroquine and azithromycin from Prof Raoult study

https://www.mediterranee-infection.com/wp-content/uploads/2020/03/Hydroxychloroquine_final_DOI_IJAA-24-1038x553.jpg

edy 30 Mar 20 14:42 
Torquemada imo

Probably,both utter juankers,i will be back for the racing bets,reember i won't forget lets see what happens..

remember*

Fire

Don't worry, doubt it will be many days before another post appears where we find out that pilots are spraying poison over millions of people or that telecoms workers have installed a mass murder device. Terry is very proud that he has discovered a secret plan by "the elite " to murder 6bn people. I believe there is a theory on this corvid19.

If you don't want to read old threads on 5g or chemtrails (totally understand why you aren't interested) then just wait a while. Or heaven forbid Fire you could even ask him.
He doesn't seem to be shy in sharing these secret plans so I'm sure he would respond to some friendly questioning form the forum's chief of police.

odds giggilo? i'll take your horse bets. you seem to have gone selectively blind on my posts!



.
https://www.dailywire.com/news/france-officially-sanctions-drug-after-78-of-80-patients-recover-from-covid-19-within-five-days

Mar 30, 2020 -- 9:46AM, Fire-and-Ice wrote:

edy you will soon get to a quarter of a million posts mate at this rate!you must be so proud i can do passive-aggressiveness too!anyway wheres giggilo with his odds?

Somehow I'm starting to doubt you really didn't mean any ill when you started that thread the other day pointing out my post count. Not cool of you to lie.

dave, the more I think about it, the less I think it's Torquemada. In addition to the lack of emojis, Torquemada, regardless of you think of his politics, was reasonably intelligent.

Fire-and-Ice has a streak of Baphornet to him though. The gutter talk, the vindictiveness, the obvious lack of any remote intelligence. If it isn't him directly, it's his twin brother.

I'm asking for odds on THIS issue giggilo! Then I'll accomodate your horse bets!
Don't run off!
If i didn't know better..........

Thank you for your kind words edy.
The mask has slipped
Its quite simple
I'm backing the french and their doctors etc
You aren't.
I'm a gambler and want a bet.
So now you insult me?
Swine

You are welcome

I've no interest in politics btw

Tends to clouds one's judgement on other issues.

Seems to me on here if a politician you hate (yeah these weirdo hate) says something, it doesn't matter what they say and how truthful the comment is they will automatically disagree with it. That is ridiculous imo.
How can  one reason with these people?
I had a go and have had a pretty crap time tbh!
Thank god the pack are absolutely powerless in this fleeting life.


Won't take a bet either
Get on mumsnet you swine

No ones going to lay odds on something they know nothing about,lets just stick to the racing now remember no hiding when i comback
like all the rest do..

so finally we reach an epiphany. giggilo wont bet on something he knows nothing about!
I believe the condition was you accomodate me on odds on this cure and i reciprocate with taking your horsey bets
You seem blind to the 1st condition giggs?
Get to spec savers fella

Anyway enough of this fella nonsense.

.
https://www.dailywire.com/news/france-officially-sanctions-drug-after-78-of-80-patients-recover-from-covid-19-within-five-days

Who was the one who started all the odds nonsense again?

Me. I'm the only on here who bets. Gotta be me
I back my views with cash edy

Me never betting doesn't make me a worse human than you. While this might be news to you, even if you've been around with another nickname before, it's actually a well-known fact on this forum for the better part of ten years that I never bet.

I'm not posting the link below to be annoying I just don't want people being put off this thread with the bickering.

Spread a little hope.
Anyone know what shares to buy in case this french cure works?
This is another form of betting edy ^^^ sorry about that


.
https://www.dailywire.com/news/france-officially-sanctions-drug-after-78-of-80-patients-recover-from-covid-19-within-five-days

See e.g

By edy on 28 Nov 13 16:05
Never had a bet in all me life.

By mouse trap on 22 Oct 14 20:45
poor edy, how can you laugh?oh, edy never bets

okay edy. i didn't know you don't gamble.

Have some posts disappeared from the start of this thread?
That's odd.
Now how did that happen?

Looks the same comparing this tab (which has had the thread opened since 1pm or so) to the thread opened again in a new tab. Any messages you are missing in particular?

The first post on this thread mentions 'the demo rats hate it'
I'm positive that wasn't the first post when I 1st read this thread.
I may be wrong

Ignore the last message edy.

What price Johnson+ Johnson has found a successful vaccine Fire and Ice?

You weren't quick enough lapsy

The race for the cure hots up as the pharma giant secures a lucrative vaccine deal with the US government.

The US government has awarded a $456 million contract to Johnson & Johnson’s pharmaceutical arm Janssen for a coronavirus vaccine, despite the company having not yet begun clinical trials for the drug. It followed a $150 million contract with Janssen, made the previous week, for a “new antiviral” for COVID-19.


6/4 now.
My tinpot firm should be at least 100s now these are involved!
Care to oblige me gigolooooo?

.
https://www.leadersleague.com/en/news/johnson-johnson-scores-456m-coronavirus-contract

Story of my life (not being quick enough),very hopeful signs though long way down the road.

Thanks for posting something optimistic Lapsy

Feeling a lot more optimistic,it will be bleak for the next few weeks though but no denying the measures re social distancing are working with a daily infection rate gone from 25%ist to around 10%.
C'mon the world!

.

try it with bleach ?

Fire and ice has got 3 tonne of it in a skip in his back garden,tenner a tonne.

Does he own shares?

On a kick back?

Positive test not revealed?

Just a nutter?


All of the above?

He does coincidentally own shares, but it's probably just that he gambled on something he was told by some quacksalver and wanted to look genius if it had been proven true.

and he is now holding onto it with his dear life.

Article from the British Medical Journal.

Rapid Response:
Re: Chloroquine and hydroxychloroquine in covid-19
Dear Editor,

The fundamental correctness in this piece cannot be disputed. Trumpian calls for wider use of chloroquine cannot be heeded until efficacy and safety are appropriately assured. That of course is what clinical trials are for.

Nevertheless, I suggest that at such a particular moment in our time, even a professional submission such as this is, should at least acknowledge the necessary influence of urgency. The speed of a convoy is the speed of the slowest ship. PHE, together with the author here, are on the bridge of that ship.

That studies to date have all employed drug doses that err on the side of plenty (although the South Koreans moderated the doses somewhat) is not surprising when the goal is to realise a clear clinical effect. But that of course raises the likelihood of poorly tolerated side effects. This, together with the author's overly pessimistic worries that chloroquine may accelerate illness progression (as per previous trials against other viruses), leads to skewed viewpoint on the emerging facts.

The author is really saying "Whoa!... not so fast! This thing has nasty side effects and might make the disease worse. Let's stick with our tightly controlled trials and see what they throw up in 12 months."

An alternate, more helpful approach might be to acknowledge what we already know about chloroquine and this SARS-CoV-2.

We know that the in-vitro studies suggested efficacy could be achieved with 500mg chloroquine phosphate per day. Yet the authors acknowledged that didn't take account of the particularly heavy sequestration of the drug in lung, liver and spleen. With such a lengthy half-life there is good reason to believe that a lower daily dose is more likely to be optimal for effect, tolerance and safety. Those trials indicated a role for the drug as prophylactic agent and early treatment.

So, whilst acknowledging that in vivo studies to date have been suboptimal in terms of construct and data reporting, there is still enough coming back to us to build reasonable confidence that there’s no evidence of disease exacerbation under studied conditions. This is important.

Certainly, trials should continue. I suggest that the evidence to date (such as it is) is largely positive for the use of chloroquine against SARS-CoV-2.

What’s needed is a large cohort study using chloroquine in dosage which brings good potential for clinical effect but with minimal risk. Surely the most elegant plan for optimal repurposing of this inexpensive drug is to employ doses already known to be universally safe.

That elegant plan indicates a prophylactic dose of 500mg Chloroquine phosphate taken once weekly (same as existing antimalarial chemoprophylaxis). For early treatment, chloroquine phosphate 500mg is taken on day 1, 3, 5 and then only on day 7 and 9 if clinical symptoms endure. The maximum total chloroquine load is 2.5g, taken over 9 days. This equates to the total dose used to safely treat non falciparum malaria over 48 hours (25mg/kg of chloroquine base equals 40mg/kg chloroquine phosphate).

These are overwhelmingly safe doses and yet still respect the values suggested from in-vitro trials.

In 2006, Dr Christopher J M Whitty (then consultant physician, now a Professor and Chief Medical Officer (Eng) and Chief Medical Adviser to UK Gov) had his paper published in the BMJ: "Malaria: an update on treatment of adults in non-endemic countries."
Therein Dr Whitty describes the 'non-falciparum' malaria treatment dose of chloroquine phosphate (40mg/kg over just 48hours):

"This works rapidly and reliably where there is no resistance, is safe in usual doses, and is well tolerated. It is considered safe in pregnancy.
Side effects—It can cause gastritis and mild abdominal pain. It can cause itching in some people of African ethnicity (mechanism unknown)."

Just so we agree, "safe in pregnancy" means very safe.

With such in mind, this week I surveyed 43 clinical colleagues using WhatsApp groups. These were GPs and secondary care clinicians. I asked whether they’d be willing to volunteer for an NHS-wide cohort study, using chloroquine as a medical countermeasure against COVID 19 (prophylaxis and treatment in the doses already advised). I received 37 replies. All 37 stated yes. The most frequent reason given was "potential benefit outweighs minimal risk."

That 86% of doctors would wish to take chloroquine as a medical countermeasure should not come as a surprise. Unlike the author, those doctors do acknowledge the presence of urgency:

We are faced with a fast-moving pandemic with an unacceptably high mortality and morbidity. Unfortunately, front line clinicians will be hugely over-represented in those statistics. They also understand the nature of clinical trials and the concept of risk versus benefit.

So, with written permission from Nominet-UK, I have launched a petition/campaign from my not-for-profit website (for patient information purposes): http://thevirus.uk
There is also a link there to the campaign at change.org http://chng.it/h64H785wCB

This petition is aimed at PHE and Gov Dept Health & SC. I request the creation of a large NHS cohort study with chloroquine being offered as medical countermeasure for all front-facing NHS staff. The control cohort selects itself (staff who decline or who have contraindications, not including those with CV contraindication).

This study should be created with speed. There is minimal due diligence required to repurpose a drug for trial use with doses already proven to be safe ... especially when the trial participants are cognizant of the nature of such a study and stand to benefit directly from any positive therapeutic impact.

In the long grass, several months down the line, we may learn that chloroquine wasn't the optimal anti-viral drug for COVID 19. Perhaps one of the more targeted agents will ultimately take that crown. But if chloroquine delivers on its early promise and prevents mortal disease progression in our brave front-line colleagues, then who gets the crown doesn't matter.

So people, don't panic. But acknowledging the urgency in this predicament is important. PHE need to seize the nettle and offer something that might just save our families and friends at the front-line.

Dr Philip L Davies
MRCGP

Trump seems confused about when he started taking it


A.... 7-10 days ago
B.... Over two weeks ago


Maybe this isn't unusual with trump
but some folk doubt he's even taking it.

the man is a coward he wouldnt take any drug that he thought had any chance that it could harm him in anyway

Stopping taking it now he's punted on his supplies

.